Here is a look at the top matchups for today’s season opener as No. 12 Clemson host Wofford for a 12:30 p.m. kickoff in Death Valley.

Clemson’s defensive front vs. Wofford’s offensive line: This is the area that will tell all of us what the flow of the game is going to be like. If the Tigers young defensive tackles can avoid being taken off their feet than Clemson can get control of this game early, but the Tigers will play as many as nine true and redshirt freshmen on the defensive side, including Albert Huggins and Christian Wilkins upfront. Scott Pagano, a sophomore, also has limited playing experience on the defensive line. If Clemson can stay on its feet, the defensive front is too big and quick for Wofford’s smaller offensive line to keep up with. Advantage: Clemson

Deshaun Watson vs. Wofford secondary: Last year, the Terriers allowed 222 yards per game and a completion percentage of 68 percent. Watson completed 68 percent of his passes in this his five starts and averaged nearly 300 yards a game through the air. Advantage: Clemson

Clemson’s offensive line vs. Wofford’s defensive front: The Tigers average about 300 pounds across the front, while Wofford’s defensive front averages 280 pounds. The Terriers run a 3-4 scheme. They like to stand the linemen up and try to clog the running lanes. It’s not an aggressive 3-4, though they will try to blitz off the edges to create pressure. This should be a good warm up game for left tackle Mitch Hyatt as he becomes the first freshman left tackle to start the season since 1944. Fellow true freshman Jake Fruhmorgen, who backs up Joe Gore on the right side, should also get a nice dry run if the Tigers are able to jump out in front. Advantage: Clemson

Clemson’s linebackers vs. Wofford’s running backs: The Tigers starting linebacker in Ben Boulware, B.J. Goodson and Travis Blanks will be fine, but this game is about getting some of those young talented backers in Jalen Williams and Kendall Joseph some playing time. That is where the Tigers could struggle, especially against a team like Wofford, whose offensive linemen, tight ends and running backs specialize in cutting defenders. But Clemson has talent and ultimately I believe its talent will overtake Wofford’s scheme, though the Terriers will give them fits. Advantage: Clemson

Bottom line: Wofford is very well coached and always plays hard. That is a tribute to head coach Mike Ayers, a former Marine. The Terriers will do that again today and I suspect they will give the Tigers a run for their money. But in the end, Clemson’s big-play offense and Watson will be too much for Wofford to overcome. The Tigers should win this with ease. Prediction: Clemson 45, Wofford 10