For the second straight week, Clemson is a double-digit favorite on the road.

The Tigers (2-3, 1-2 ACC) are currently a 12.5-point favorite over Boston College (1-4, 0-3 ACC), according to FanDuel Sportsbook.

Clemson was a 14.5-point favorite entering Saturday’s game at North Carolina, and the Tigers rolled past the Tar Heels in Chapel Hill, 38-10.

Meanwhile, Boston College was pummeled in a road contest at Pitt, losing 48-7.

This Saturday’s game between Clemson and BC at Alumni Stadium in Chestnut Hill, Mass., is set to kick off at 7:30 p.m. and will be televised on ACC Network.

Clemson has won its last 12 meetings with Boston College, including a 5-0 mark in games played in Chestnut Hill since 2011.

The game will be Clemson’s first against current Boston College head coach Bill O’Brien. The Tigers were undefeated against the Eagles’ two previous head coaches, including a 7-0 mark against Steve Addazio and a 3-0 record against Jeff Hafley.